CrohnDB: A Web Database for Expression Profiling of Protein-Coding and Long Non-Coding RNA Genes in Crohn Disease

Crohn disease (CD) is a type of inflammatory bowel that causes inflammation in the digestive tract. Cases CD are increasing worldwide, calling for more research to elucidate pathogenesis CD. For this purpose, usage RNA-sequencing (RNA-seq) technique increasingly appreciated, as it captures RNA expression patterns at particular time point high-throughput manner. Although many RNA-seq datasets generated from patients and compared those healthy donors, most these analyzed only protein-coding genes, leaving non-coding RNAs (ncRNAs) undiscovered. Long (lncRNAs) any ncRNAs longer than 200 nucleotides. Interest studying lncRNAs rapidly, bind other macromolecules (DNA, RNA, and/or proteins) finetune signaling pathways. To fill gap knowledge about CD, we performed secondary analysis published data donors identify lncRNA genes their changes. further facilitate built web database, CrohnDB, provide one-stop-shop profiling donors.